Corneal neovascularization: molecular events and therapeutic options.

  title={Corneal neovascularization: molecular events and therapeutic options.},
  author={Yadollah Shakiba and Kamran Mansouri and Delnia Arshadi and Nima Attaran Rezaei},
  journal={Recent patents on inflammation & allergy drug discovery},
  volume={3 3},
Corneal neovascularization (NV) is a significant complication of numerous infectious and non-infectious ocular surface disorders. Presence of newly formed blood vessels in the cornea can compromise clarity and therefore vision. Various growth factors and proteinases seem to be involved in the corneal NV. During corneal injury, angiogenic factors are released from corneal epithelial and stromal cells as well as infiltrating immune cells like macrophages. In fact, the balance between angiogenic… CONTINUE READING

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