Corneal antinociceptive effect of (-)-α-bisabolol

@inproceedings{Teixeira2017CornealAE,
  title={Corneal antinociceptive effect of (-)-α-bisabolol},
  author={Gisele Façanha Di{\'o}genes Teixeira and Fl{\'a}vio Nogueira da Costa and Adriana Rolim Campos},
  booktitle={Pharmaceutical biology},
  year={2017}
}
CONTEXT (-)-α-Bisabolol (BISA) is a sesquiterpene alcohol widely used as scent in cosmetic preparations, perfumes, shampoos, toilet soaps and other toiletries with potential for use in the pharmaceutical area. OBJECTIVE To evaluate the corneal antinociceptive efficacy of BISA and to analyze the best solubilizing agent. MATERIALS AND METHODS Acute corneal nociception was induced by the local application of hypertonic saline (5 M NaCl; 20 μL) to the corneal surface of Swiss mice (n = 8/group… CONTINUE READING

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