Coresistance to neomycin and kanamycin by mutations in an Escherichia coli locus that affects ribosomes.


Mutant strains resistant to neomycin or to kanamycin sulfate were isolated from Escherichia coli K-12. Nine mutants were analyzed; all were resistant to both antibiotics (about 150 and 100 mug/ml, respectively), and were designated nek. In the mutant strains, the ribosomes are changed from those of the parental strain; for when they were used in assays for… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.