Coreplication of the major genotype group members of porcine circovirus type 2 as a prerequisite to coevolution may explain the variable disease manifestations.

@article{Khaiseb2011CoreplicationOT,
  title={Coreplication of the major genotype group members of porcine circovirus type 2 as a prerequisite to coevolution may explain the variable disease manifestations.},
  author={Siegfried Khaiseb and Titus Sydler and Dieter Zimmermann and Andreas Pospischil and Xaver Sidler and Enrico Brugnera},
  journal={Journal of virology},
  year={2011},
  volume={85 21},
  pages={11111-20}
}
A member of the family Circoviridae, porcine circovirus type 2 (PCV2), is associated with postweaning multisystemic wasting syndrome (PMWS), a recent emerging disease worldwide. PCV2 is also found in clinically asymptomatic animals. This paradoxical finding makes the syndrome etiology challenging. We developed new assays to study PCV2 with links to syndrome etiology. For analysis, we used PCV2-infected tissues from subclinically infected and diseased piglets. We compared antigen- and PCV2 DNA… CONTINUE READING

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