Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter.

@article{Berrard1995CoregulationOT,
  title={Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter.},
  author={Sylvie Berrard and H{\'e}l{\`e}ne Varoqui and Riccardo Cervini and Maurice Isra{\"e}l and Jacques Mallet and Marie Françoise Diebler},
  journal={Journal of neurochemistry},
  year={1995},
  volume={65 2},
  pages={939-42}
}
The gene encoding the vesicular acetylcholine transporter (VAChT) has recently been localized within the first intron of the gene encoding choline acetyltransferase (ChAT) and is in the same transcriptional orientation. These two genes, whose products are required for the expression of the cholinergic phenotype, could therefore be coregulated. We thus tested the effects on VAChT gene expression of the cholinergic differentiation factor/leukemia inhibitory factor and retinoic acid, both of which… CONTINUE READING

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