Core symptoms of major depressive disorder: relevance to diagnosis and treatment

  title={Core symptoms of major depressive disorder: relevance to diagnosis and treatment},
  author={Sidney H. Kennedy},
  booktitle={Dialogues in clinical neuroscience},
The construct of major depressive disorder makes no etiological assumptions about populations with diverse symptom clusters. "Depressed mood" and "loss of interest or pleasure in nearly all activities" are core features of major depressive episode, though a strong case can be made to pay increasing attention to symptoms of fatigue, sleep disturbance, anxiety, and neurocognitive and sexual dysfunction in the diagnosis and evaluation of treatment outcome. Mood, guilt, work, and interest, as well… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 63 references

Use of glucose metabolism positron emission tomography to predict antidepressant response to cognitive behavioural therapy or venlafaxine

JZ Konarski, SH Kennedy, ZV Segal
J Psychiatry Neurosci • 2008
View 1 Excerpt

Sleep and circadian rhythms in mood disorders.

Acta psychiatrica Scandinavica. Supplementum • 2007
View 1 Excerpt

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