Core-shell-corona micelle stabilized by reversible cross-linkage for intracellular drug delivery.

@article{Wang2010CoreshellcoronaMS,
  title={Core-shell-corona micelle stabilized by reversible cross-linkage for intracellular drug delivery.},
  author={Yucai Wang and Yang Li and Tian-meng Sun and Meng-Hua Xiong and Juan Wu and Yi-Yan Yang and Jun Wang},
  journal={Macromolecular rapid communications},
  year={2010},
  volume={31 13},
  pages={1201-6}
}
Reversibly cross-linked core-shell-corona micelles based on a triblock copolymer composed of poly(aliphatic ester), polyphosphoester, and poly(ethylene glycol) are reported. The triblock copolymer is synthesized through consecutive ring-opening polymerization of ε-caprolactone and 2,4-dinitrophenylthioethyl ethylene phosphate, followed by conjugation of poly(ethylene glycol). After deprotection under mild conditions, the amphiphilic polymer forms core-shell-corona micelles with free thiols in… CONTINUE READING

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