Core promoters of the penicillin biosynthesis genes and quantitative RT-PCR analysis of these genes in high and low production strain of Penicillium chrysogenum

@article{midk2010CorePO,
  title={Core promoters of the penicillin biosynthesis genes and quantitative RT-PCR analysis of these genes in high and low production strain of Penicillium chrysogenum},
  author={Roman {\vS}mid{\'a}k and Martin Jop{\vc}{\'i}k and Martina Kralovi{\vc}ov{\'a} and J. Gajdo{\vs}{\'i}kov{\'a} and Jan Kormanec and Jozef Timko and Jan Turna},
  journal={Folia Microbiologica},
  year={2010},
  volume={55},
  pages={126-132}
}
The transcription start points of the penicillin biosynthesis genes from Penicillium chrysogenum were mapped using the primer extension method. For each of the three genes consensus sequences of the core promoter elements were identified, supporting the notion that the basal transcription of these genes is mediated separately. Interestingly, transcription start of the pcbC gene is located within the potential Inr element with no TATA box-like sequence being found at expected position. This is… CONTINUE READING
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