Core promoters and transcriptional control.

  title={Core promoters and transcriptional control.},
  author={Carl D. Novina and Ananda L Roy},
  journal={Trends in genetics : TIG},
  volume={12 9},
Many biological processes are controlled, spatially and temporally, at the level of transcription. Thus, understanding the mechanisms of transcriptional regulation of gene expression is critical in deciphering the molecular modes of differentiation and development of a eukaryotic cell. Transcriptional control is mediated largely through interactions of regulatory transcription factors with their cognate enhancer elements. The regulatory signals generated at enhancer elements are communicated to… CONTINUE READING
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