Core classification of head and neck squamous cell carcinomas: correlations between morphology, DNA ploidy and HPV infection.

@article{Kotb2010CoreCO,
  title={Core classification of head and neck squamous cell carcinomas: correlations between morphology, DNA ploidy and HPV infection.},
  author={Waleed F M Amin Kotb and Christiane Blind and K. Friedrich and Christiane Schewe and Zhigang Zhang and Jian Ming Zheng and Nicole Deutschman and Manuela Pacyna-Gengelbach and Manfred Dietel and Iver Petersen},
  journal={Pathology, research and practice},
  year={2010},
  volume={206 11},
  pages={768-71}
}
AIMS The study intended to reveal whether HPV infection is reflected by nuclear morphology and DNA cytometry parameters in head and neck squamous cell carcinomas (HNSCC). METHODS In total, 39 HNSCC were selected for reanalysis by histomorphology applying the core classification, DNA cytometry and HPV detection. For the core classification, HE sections were assessed by a score system to evaluate the nuclear size, the mitosis size, their variabilities and the presence of tripolar or tetrapolar… CONTINUE READING

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