Core and E antigen synthesis in rodent cells transformed with hepatitis B virus DNA is associated with greater than genome length viral messenger RNAs.

  • N. M. Gough
  • Published 1983 in Journal of molecular biology


The viral RNA sequences in a number of rodent cell lines which contain integrated hepatitis B virus DNA were examined. In one of the cell lines, which produces the hepatitis B virus surface, core and e antigens, there are four polyadenylated, cytoplasmic RNA species, estimated to be 4425, 3968, 2435 and 1054 nucleotides in length, which hybridize with… (More)