Corpus ID: 38002620

Cordycepin induces apoptosis in human neuroblastoma SK-N-BE(2)-C and melanoma SK-MEL-2 cells.

  title={Cordycepin induces apoptosis in human neuroblastoma SK-N-BE(2)-C and melanoma SK-MEL-2 cells.},
  author={Ji-Sue Baik and Haw-young Kwon and Kyoung-Sook Kim and Yong-Ki Jeong and Young-Su Cho and Y. Lee},
  journal={Indian journal of biochemistry & biophysics},
  volume={49 2},
  • Ji-Sue Baik, Haw-young Kwon, +3 authors Y. Lee
  • Published 2012
  • Biology, Medicine
  • Indian journal of biochemistry & biophysics
  • In this study, the effect of cordycepin (3'-deoxyadenosine), a major component of Cordyceps militaris, an ingredient of traditional Chinese medicine was investigated for the first time on apoptotsis in human neuroblastoma SK-N-BE(2)-C and melanoma SK-MEL-2 cells. Cordycepin significantly inhibited the proliferation of human neuroblastoma SK-N-BE(2)-C and human melanoma SK-MEL-2 cells with IC50 values of 120 microM and 80 microM, respectively. Cordycepin treatment at 120 microM and 80 microM… CONTINUE READING
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