Cord blood donor cell leukemia in recipients

@article{Greaves2006CordBD,
  title={Cord blood donor cell leukemia in recipients},
  author={Melvyn F. Greaves},
  journal={Leukemia},
  year={2006},
  volume={20},
  pages={1633-1634}
}
CD34 cell dose and NK30, but not day-30 CD3þ cell count, were predictors of transplant outcome and CD34 cell dose correlated with day-30 NK counts. The conclusion was that higher transplanted CD34 cell doses may improve outcomes by increasing early recovery of NK cells. These observations suggest that GVL activity early after HLA-matched SCT may be exerted more by NK cells than by T cells. However, it is not obvious how such NK cells would exert GVL, since 30 days after transplant most NK cells… CONTINUE READING