Coral reefs, forests, and thermal vents: the worldwide exploration of nature for novel antitumor agents.

@article{Cragg1997CoralRF,
  title={Coral reefs, forests, and thermal vents: the worldwide exploration of nature for novel antitumor agents.},
  author={Gordon M. Cragg and David J. Newman and Raymond B. Weiss},
  journal={Seminars in oncology},
  year={1997},
  volume={24 2},
  pages={156-63}
}
Nature has been a source of medicinal treatments for thousands of years, and plant-based systems continue to play an essential role in the primary health care of 80% of the world's population. Nature has provided many of the effective anticancer agents in current use, such as the microbially derived drugs, dactinomycin, bleomycin, and doxorubicin, and the plant-derived drugs vinblastine, irinotecan, topotecan, etoposide, and paclitaxel. The search for novel antitumor agents from natural sources… CONTINUE READING