• DOI:10.1038/nature07458
Corpus ID: 4377899

Copy-number variations associated with neuropsychiatric conditions

@article{Cook2008CopynumberVA,
  title={Copy-number variations associated with neuropsychiatric conditions},
  author={E. Cook and S. Scherer},
  journal={Nature},
  year={2008},
  volume={455},
  pages={919-923}
}

E. Cook, S. Scherer

Published 2008

Biology, Medicine

Nature

Neuropsychiatric conditions such as autism and schizophrenia have long been attributed to genetic alterations, but identifying the genes responsible has proved challenging. Microarray experiments have now revealed abundant copy-number variation — a type of variation in which stretches of DNA are duplicated, deleted and sometimes rearranged — in the human population. Genes affected by copy-number variation are good candidates for research into disease susceptibility. The complexity of… CONTINUE READING

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