Copy-number variations associated with neuropsychiatric conditions

@article{Cook2008CopynumberVA,
  title={Copy-number variations associated with neuropsychiatric conditions},
  author={Edwin H. Cook and Stephen W. Scherer},
  journal={Nature},
  year={2008},
  volume={455},
  pages={919-923}
}
Neuropsychiatric conditions such as autism and schizophrenia have long been attributed to genetic alterations, but identifying the genes responsible has proved challenging. Microarray experiments have now revealed abundant copy-number variation — a type of variation in which stretches of DNA are duplicated, deleted and sometimes rearranged — in the human population. Genes affected by copy-number variation are good candidates for research into disease susceptibility. The complexity of… 
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