Copy-number variations associated with neuropsychiatric conditions

  title={Copy-number variations associated with neuropsychiatric conditions},
  author={E. Cook and S. Scherer},
  • E. Cook, S. Scherer
  • Published 2008
  • Biology, Medicine
  • Nature
  • Neuropsychiatric conditions such as autism and schizophrenia have long been attributed to genetic alterations, but identifying the genes responsible has proved challenging. Microarray experiments have now revealed abundant copy-number variation — a type of variation in which stretches of DNA are duplicated, deleted and sometimes rearranged — in the human population. Genes affected by copy-number variation are good candidates for research into disease susceptibility. The complexity of… CONTINUE READING
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