Copy number variation-based polymorphism in a new pseudoautosomal region 3 (PAR3) of a human X-chromosome-transposed region (XTR) in the Y chromosome

@article{Veerappa2013CopyNV,
  title={Copy number variation-based polymorphism in a new pseudoautosomal region 3 (PAR3) of a human X-chromosome-transposed region (XTR) in the Y chromosome},
  author={Avinash M. Veerappa and P. Padakannaya and N. Ramachandra},
  journal={Functional & Integrative Genomics},
  year={2013},
  volume={13},
  pages={285-293}
}
A 3.5-Mb region of the X chromosome underwent duplication and transposition to the Y chromosome ~5–6 Mya. This X-transposed-region (XTR) originated at Xq21.3 and was inserted at Yp11.2. The two locations have 98.78 % homology and a high concentration of tandem repeats. In whole-genome scans of ten large families with dyslexic members, we identified transposed blocks comprising >102 kb of the Yp11.2 region in its homologous region at Xq21.3 in three females from three different families… Expand
35 Citations
Genetic Diversity on the Human X Chromosome Does Not Support a Strict Pseudoautosomal Boundary
  • 28
  • PDF
The fragile Y hypothesis: Y chromosome aneuploidy as a selective pressure in sex chromosome and meiotic mechanism evolution
  • 15
  • PDF
The Eutherian Pseudoautosomal Region
  • 46
Global patterns of large copy number variations in the human genome reveal complexity in chromosome organization.
  • 1
  • PDF
Genetics of the human Y chromosome and its association with male infertility
  • 76
Genome‐wide copy number scan identifies disruption of PCDH11X in developmental dyslexia
  • 35
...
1
2
3
4
...

References

SHOWING 1-10 OF 27 REFERENCES
The Human Pseudoautosomal Region (PAR): Origin, Function and Future.
  • 191
  • Highly Influential
Structural variation on the short arm of the human Y chromosome: recurrent multigene deletions encompassing Amelogenin Y.
  • 113
  • PDF
The DNA sequence of the human X chromosome
  • 1,004
  • Highly Influential
  • PDF
Gene duplications as a recurrent theme in the evolution of the human pseudoautosomal region 1: isolation of the gene ASMTL.
  • 45
  • PDF
The human pseudoautosomal regions: a review for genetic epidemiologists
  • 57
  • PDF
Abundant gene conversion between arms of palindromes in human and ape Y chromosomes
  • 550
  • PDF
Accelerated evolution of Protocadherin11X/Y: A candidate gene‐pair for cerebral asymmetry and language
  • N. Williams, J. Close, Maria Giouzeli, T. Crow
  • Biology, Medicine
  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • 2006
  • 93
  • Highly Influential
...
1
2
3
...