• DOI:10.1007/s10142-013-0323-6
Corpus ID: 13443194

Copy number variation-based polymorphism in a new pseudoautosomal region 3 (PAR3) of a human X-chromosome-transposed region (XTR) in the Y chromosome

@article{Veerappa2013CopyNV,
  title={Copy number variation-based polymorphism in a new pseudoautosomal region 3 (PAR3) of a human X-chromosome-transposed region (XTR) in the Y chromosome},
  author={Avinash M. Veerappa and P. Padakannaya and N. Ramachandra},
  journal={Functional & Integrative Genomics},
  year={2013},
  volume={13},
  pages={285-293}
}

Avinash M. Veerappa, P. Padakannaya, N. Ramachandra

Published 2013

Biology, Medicine

Functional & Integrative Genomics

A 3.5-Mb region of the X chromosome underwent duplication and transposition to the Y chromosome ~5–6 Mya. This X-transposed-region (XTR) originated at Xq21.3 and was inserted at Yp11.2. The two locations have 98.78 % homology and a high concentration of tandem repeats. In whole-genome scans of ten large families with dyslexic members, we identified transposed blocks comprising >102 kb of the Yp11.2 region in its homologous region at Xq21.3 in three females from three different families… CONTINUE READING

View on Springer

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed