Copy number polymorphism of endogenous feline leukemia virus-like sequences.

  title={Copy number polymorphism of endogenous feline leukemia virus-like sequences.},
  author={R. Tandon and V. Cattori and B. Willi and M. Meli and M. A. Gomes-Keller and H. Lutz and R. Hofmann-Lehmann},
  journal={Molecular and cellular probes},
  volume={21 4},
  • R. Tandon, V. Cattori, +4 authors R. Hofmann-Lehmann
  • Published 2007
  • Biology, Medicine
  • Molecular and cellular probes
  • In the cat genome, endogenous feline leukemia virus (enFeLV) exists as multiple, nearly full-length proviral sequences. Even though no infectious virus is produced from enFeLV sequences, transcription and translation have been demonstrated in tissues of healthy cats and in feline cell lines. To test the hypothesis that the enFeLV loads play a role in exogenous FeLV-A infection and pathogenesis, we designed three real-time PCR assays to quantify U3 and env enFeLV loads (two within U3 amplifying… CONTINUE READING
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