Copy number increase of oncoprotein CIP2A is associated with poor patient survival in human head and neck squamous cell carcinoma.

Abstract

BACKGROUND CIP2A, an inhibitor of PP2A tumour suppressor function, is a widely overexpressed biomarker of aggressive disease and poor therapy response in multiple human cancer types. METHODS CIP2A and DPPA4 copy number alterations and expression were analysed by fluorescence in situ hybridisation (FISH) and immunohistochemistry (IHC) in different cell… (More)
DOI: 10.1111/jop.12372

Topics

9 Figures and Tables

Cite this paper

@article{Routila2016CopyNI, title={Copy number increase of oncoprotein CIP2A is associated with poor patient survival in human head and neck squamous cell carcinoma.}, author={Johannes Routila and T{\"{u}rker Bilgen and Outi R. Saram{\"a}ki and Reidar Axel Grenman and Tapio Visakorpi and Jukka Westermarck and Sami Ventel{\"a}}, journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology}, year={2016}, volume={45 5}, pages={329-37} }