Copy number gains on 22q13 in adenoid cystic carcinoma of the salivary gland revealed by comparative genomic hybridization and tissue microarray analysis.

Abstract

Adenoid cystic carcinoma (ACC) of the salivary gland is a neoplasm characterized by slow but inevitable local progression and terminal hematogenous metastasis. To detect novel imbalanced chromosomal regions associated with tumorigenesis, we used chromosomal comparative genomic hybridization to screen 27 ACC. The most common aberration was copy number gain… (More)

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@article{Freier2005CopyNG, title={Copy number gains on 22q13 in adenoid cystic carcinoma of the salivary gland revealed by comparative genomic hybridization and tissue microarray analysis.}, author={Kolja Freier and Christa Flechtenmacher and Axel Walch and Sibylle Ohl and Frauke Devens and Bert Burke and Stefan Ha\ssfeld and Peter Lichter and Stefan Joos and Christof M Hofele}, journal={Cancer genetics and cytogenetics}, year={2005}, volume={159 1}, pages={89-95} }