Copy-Number Variation Genotyping of GSTT 1 and GSTM 1 Gene Deletions by Real-Time PCR

@inproceedings{RoseZerilli2009CopyNumberVG,
  title={Copy-Number Variation Genotyping of GSTT 1 and GSTM 1 Gene Deletions by Real-Time PCR},
  author={Matthew J. J. Rose-Zerilli and S J Barton and Alexander John Henderson and S O Shaheen and John W Holloway},
  year={2009}
}
BACKGROUND: Structural variation in the human genome is increasingly recognized as being highly prevalent and having relevance to common human diseases. Array-based comparative genome-hybridization technology can be used to determine copy-number variation (CNV) across entire genomes, and quantitative PCR (qPCR) can be used to validate de novo variation or assays of common CNV in disease-association studies. Analysis of large qPCR data sets can be complicated and time-consuming, however. 
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Structural variation in the human genome.

The New England journal of medicine • 2007

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