Copy Number Variants and Common Disorders: Filling the Gaps and Exploring Complexity in Genome-Wide Association Studies

@article{Estivill2007CopyNV,
  title={Copy Number Variants and Common Disorders: Filling the Gaps and Exploring Complexity in Genome-Wide Association Studies},
  author={Xavier Estivill and Llu{\'i}s Armengol},
  journal={PLoS Genetics},
  year={2007},
  volume={3},
  pages={1299 - 1320}
}
Genome-wide association scans (GWASs) using single nucleotide polymorphisms (SNPs) have been completed successfully for several common disorders and have detected over 30 new associations. Considering the large sample sizes and genome-wide SNP coverage of the scans, one might have expected many of the common variants underpinning the genetic component of various disorders to have been identified by now. However, these studies have not evaluated the contribution of other forms of genetic… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 100 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 89 references

Similar Papers

Loading similar papers…