Copper toxicity in gills of the teleost fish, Oreochromis niloticus: effects in apoptosis induction and cell proliferation.

@article{Monteiro2009CopperTI,
  title={Copper toxicity in gills of the teleost fish, Oreochromis niloticus: effects in apoptosis induction and cell proliferation.},
  author={Sandra Mariza Monteiro and Nuno M S dos Santos and Margarida Calejo and Ant{\'o}nio A Fonta{\'i}nhas-Fernandes and Mario de Sousa},
  journal={Aquatic toxicology},
  year={2009},
  volume={94 3},
  pages={219-28}
}
Recent in vitro studies have demonstrated that copper may induce apoptosis triggering the activation of caspase-3, a central effector of apoptotic cell death. However, the precise mechanism of copper-induced apoptosis is still unclear, even less so in Oreochromis niloticus where no caspase genes have been reported so far. This study aimed to assess the in vivo role of copper in apoptosis induction on O. niloticus gill, simultaneously contributing to elucidate the mechanism of copper-induced… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 38 references

Cortisol protects against copper induced necrosis and promotes apoptosis in fish gill chloride cells in vitro

  • J. Li, R. A. C. Lock, S. E. Wendelaar Bonga
  • Aquat . Toxicol .
  • 1998
Highly Influential
4 Excerpts

Molecular mechanism of copper uptake and distribution

  • M. Roméo, N. Bennani, M. Gnassia-Barelli, M. Lafaurie, J. P. Girard
  • Curr . Opin . Chem . Biol .
  • 2000
Highly Influential
4 Excerpts

History of the events leading to the formulation of the apoptosis concept

  • S. rantic, N. Mechawar, S. Reix, R. Quirion
  • Toxicology
  • 2007

Copper biochemistry and molecular biology

  • J. Lu, Y. Zheng, D. Wu, D. Sun, Q. Shan, S. Fan
  • Am . J . Clin . Nutr .
  • 2006
1 Excerpt

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