Copper supplementation increases yeast life span under conditions requiring respiratory metabolism.

@article{Kirchman2007CopperSI,
  title={Copper supplementation increases yeast life span under conditions requiring respiratory metabolism.},
  author={Paul A. Kirchman and Gabriela Botta},
  journal={Mechanisms of ageing and development},
  year={2007},
  volume={128 2},
  pages={187-95}
}
To further exploit yeast as a model for cellular aging we have modified the replicative life span assay to force respiration, by replacing glucose with the non-fermentable carbon source glycerol. The growth rates of several different strains varied greatly, with doubling times ranging from 2.7 to 7 h. Life spans of all strains were lower on media containing glycerol than on media containing glucose. However, supplementation of glycerol-containing media with copper resulted in increases in life… CONTINUE READING

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