Copper metabolism in analbuminaemic rats fed a high-copper diet.

  title={Copper metabolism in analbuminaemic rats fed a high-copper diet.},
  author={Shiguang Yu and Gerard J. van den Berg and Anton Christian Beynen},
  journal={Comparative biochemistry and physiology. Part A, Physiology},
  volume={110 3},
Copper metabolism in male Nagase analbuminaemic (NA) rats was compared with that in male Sprague Dawley (SD) rats fed purified diets containing either 5 or 100 mg Cu/kg diet. Dietary copper loading increased hepatic and kidney copper concentrations in both strains to the same extent, but baseline values were higher in the NA rats. There was no strain difference in true and apparent copper absorption nor in faecal endogenous and urinary copper excretion. NA rats had higher levels of… CONTINUE READING