Copper inducing Aβ42 rather than Aβ40 nanoscale oligomer formation is the key process for Aβ neurotoxicity.

Abstract

Copper is known to be a critical factor in Alzheimer's disease (AD) pathogenesis, as it is involved in amyloid-β (Aβ) peptide related toxicity. However, the relationship between neurotoxicity and Aβ peptide in the presence of copper remains unclear. The effect of copper has not been clearly differentiated between Aβ42 and Aβ40, and it is still debated… (More)
DOI: 10.1039/c1nr11029b

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Cite this paper

@article{Jin2011CopperIA, title={Copper inducing Aβ42 rather than Aβ40 nanoscale oligomer formation is the key process for Aβ neurotoxicity.}, author={Lu Jin and Wei-hui Wu and Qiu-Ye Li and Yufen Zhao and Yanmei Li}, journal={Nanoscale}, year={2011}, volume={3 11}, pages={4746-51} }