Copper induces luteinizing hormone release and desensitization of pituitary gonadotropes.

Abstract

Copper stimulated LH release from cultured rat pituitary cells in a dose-and time-dependent manner. After 4 h of incubation with 10 mu M Cu2+, LH release was stimulated by 3-fold. The release of LH stimulated by Cu2+ was Ca2+ dependent, thus excluding the possibility that the releasing activity of this divalent cation was due to a toxic effect on pituitary… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.