Copper-facilitated Suzuki reactions: application to 2-heterocyclic boronates.

  title={Copper-facilitated Suzuki reactions: application to 2-heterocyclic boronates.},
  author={James Z Deng and Daniel V Paone and Anthony T Ginnetti and Hideki Kurihara and Spencer D Dreher and Steven A Weissman and Shaun R. Stauffer and Christopher S Burgey},
  journal={Organic letters},
  volume={11 2},
The palladium-catalyzed Suzuki-Miyaura reaction has been utilized as one of the most powerful methods for C-C bond formation. However, Suzuki reactions of electron-deficient 2-heterocyclic boronates generally give low conversions and remain challenging. The successful copper(I) facilitated Suzuki coupling of 2-heterocyclic boronates that is broad in scope is reported. Use of this methodology affords greatly enhanced yields of these notoriously difficult couplings. Furthermore, mechanistic… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…