Copper complexes as anticancer agents.

  title={Copper complexes as anticancer agents.},
  author={C. M. Asinari di San Marzano and Maura Pellei and Francesco Tisato and Carlo Santini},
  journal={Anti-cancer agents in medicinal chemistry},
  volume={9 2},
Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is regarded as one of the most effective drugs, even if severe toxicities and drug resistance phenomena limit its clinical use. Therefore, in recent years there has been a rapid expansion in research and development of novel metal-based anticancer drugs to improve clinical effectiveness, to reduce general toxicity and to broaden the spectrum of activity. The variety of metal ion functions in biology has… CONTINUE READING

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