Copper-catalyzed one-pot synthesis of N-aryl oxazolidinones from amino alcohol carbamates.

@article{Mahy2014CoppercatalyzedOS,
  title={Copper-catalyzed one-pot synthesis of N-aryl oxazolidinones from amino alcohol carbamates.},
  author={William Mahy and Pawel K. Plucinski and Christopher G Frost},
  journal={Organic letters},
  year={2014},
  volume={16 19},
  pages={5020-3}
}
An efficient sequential intramolecular cyclization of amino alcohol carbamates followed by Cu-catalyzed cross-coupling with aryl iodides under mild conditions has been developed. The reaction occurred in good yields and tolerated aryl iodides containing functionalities such as nitriles, ketones, ethers, and halogens. Heteroaryl iodides and substituted amino alcohol carbamates were also well tolerated.