Copper and iron-induced oxidative damage in non-tumor bearing LEC rats.

@article{Ma1997CopperAI,
  title={Copper and iron-induced oxidative damage in non-tumor bearing LEC rats.},
  author={Ying Liang Ma and Donglu Zhang and Teruyuki Kawabata and Takahiro Kiriu and Shinya Toyokuni and Kazuo Uchida and Shigeru Okada},
  journal={Pathology international},
  year={1997},
  volume={47 4},
  pages={203-8}
}
The copper and iron status in the liver of non-tumor bearing Long-Evans Cinnamon (LEC) rats (average age 17 months) was investigated. A direct quantitation of loosely-bound copper and iron was also investigated by using a chelating agent, nitrilotriacetic acid (NTA-chelatable free copper and iron). Besides the total copper and iron contents, the level of NTA-chelatable free copper was also higher in LEC rats than in LEA rats (P<0.05). But for the free iron level there was no significant… CONTINUE READING

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