Copper addition prevents the inhibitory effects of interleukin 1-β on rat pancreatic islets

Abstract

Since copper [Cu(II)] is a necessary cofactor for both intra-mitochondrial enzymes involved in energy production and hydroxyl scavenger enzymes, two hypothesised mechanisms for action of interleukin-Iβ (IL-1β), we studied whether CU(II) addition could prevent the inhibitory effect of IL-1β on insulin release and glucose oxidation in rat pancreatic islets… (More)
DOI: 10.1007/BF02369351

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@article{Vinci1995CopperAP, title={Copper addition prevents the inhibitory effects of interleukin 1-β on rat pancreatic islets}, author={Chiara Vinci and Valeria Caltabiano and Anna Maria Santoro and Agata Maria Rabuazzo and Marzia Buscema and Roberto Purrello and Enrico Rizzarelli and Riccardo Vigneri and Dr. F. Purrello}, journal={Diabetologia}, year={1995}, volume={38}, pages={39-45} }