Copper Control as an Antiangiogenic Anticancer Therapy: Lessons from Treating Wilson's Disease

  title={Copper Control as an Antiangiogenic Anticancer Therapy: Lessons from Treating Wilson's Disease},
  author={G. Brewer},
  journal={Experimental Biology and Medicine},
  pages={665 - 673}
  • G. Brewer
  • Published 2001
  • Biology, Medicine
  • Experimental Biology and Medicine
  • The search for new anticopper drugs for Wilson's disease is culminating in two excellent new drugs: zinc for maintenance therapy and tetrathiomolybdate (TM) for initial therapy. Both are effective and nontoxic. TM is a very potent, fast-acting new anticopper drug and its properties may be useful well beyond Wilson's disease. Angiogenesis (new blood vessel growth) is required for tumor growth, and a sufficient level of copper appears to be required for angiogenesis. We hypothesize that there is… CONTINUE READING
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