Copper-Catalyzed Addition of H-P(O) Bonds to Arynes.

@article{Chen2016CopperCatalyzedAO,
  title={Copper-Catalyzed Addition of H-P(O) Bonds to Arynes.},
  author={Qian Chen and Xinxing Yan and Chunxiao Wen and Jiekun Zeng and Yulin Huang and Xingguo Liu and Kun Zhang},
  journal={The Journal of organic chemistry},
  year={2016},
  volume={81 19},
  pages={9476-9482}
}
An efficient P-arylation of secondary phosphine oxides has been achieved through the ligand-free copper-catalyzed addition of H-P(O) bonds to in situ generated arynes at room temperature. This transformation provides a straightforward route to the formation of the aryl-P bond with wide functional group compatibility, which produces arylphosphine oxides in… CONTINUE READING