Copper(i)-catalysed asymmetric allylic reductions with hydrosilanes.

Abstract

A copper(i)-catalysed asymmetric allylic reduction enables a regio- and stereoselective transfer of a hydride nucleophile in an SN2'-fashion onto allylic bromides. This transformation represents a conceptually orthogonal approach to allylic substitution reactions with carbon nucleophiles. A copper(i) complex based upon a chiral N-heterocyclic carbene (NHC… (More)
DOI: 10.1039/c7cc07008j

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.