Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity.

@article{Gama2011CopperIICW,
  title={Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity.},
  author={Sofia Gama and Filipa Mendes and Fernanda Marques and Isabel C Santos and M. Fernanda N. N. Carvalho and Isabel Correia and Jo{\~a}o Costa Pessoa and Ant{\'o}nio Paulo},
  journal={Journal of inorganic biochemistry},
  year={2011},
  volume={105 5},
  pages={637-44}
}
Tridentate pyrazole-containing ligands of the Schiff base type, SalPz - HL(1), Cl(2)SalPz - HL(2) and I(2)SalPz - HL(3), were used to prepare a series of new Cu(II) complexes (CuSalPz - 1, CuCl(2)SalPz - 2 and CuI(2)SalPz - 3). These new complexes have been studied by different analytical techniques (electrospray ionization mass spectrometry (ESI-MS), elemental analysis, FT-IR and EPR). The spectroscopic properties of 1-3 are consistent with the formation of Cu(II) complexes coordinated by… CONTINUE READING

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