Coparalogy: physical and functional clusterings in the human genome.

@article{Popovici2001CoparalogyPA,
  title={Coparalogy: physical and functional clusterings in the human genome.},
  author={Cornel Popovici and Magalie Leveugle and Daniel Birnbaum and François Coulier},
  journal={Biochemical and biophysical research communications},
  year={2001},
  volume={288 2},
  pages={362-70}
}
Two rounds of large-scale duplications are thought to have occurred in early vertebrate ancestry; this is now known as the "2R hypothesis." They have led to the constitution of subfamilies of paralogous genes. Chromosomal regions that contain present-day paralogs (paralogous regions or paralogons) have been identified in mammals. We show that sets of paralogons (PGs) can be assembled in a tentative "human genome paralogy map" that includes all autosomes and X. A total of 14 PGs, containing more… CONTINUE READING

From This Paper

Topics from this paper.
17 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…