CopA: An Escherichia coli Cu(I)-translocating P-type ATPase.


The copA gene product, a putative copper-translocating P-type ATPase, has been shown to be involved in copper resistance in Escherichia coli. The copA gene was disrupted by insertion of a kanamycin gene through homologous recombination. The mutant strain was more sensitive to copper salts but not to salts of other metals, suggesting a role in copper… (More)


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@article{Rensing2000CopAAE, title={CopA: An Escherichia coli Cu(I)-translocating P-type ATPase.}, author={Cornelia Rensing and Buqun Fan and Rajal Sharma and Bharati Mitra and Barry P. Rosen}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2000}, volume={97 2}, pages={652-6} }