Coordination of transposon expression with DNA replication in the targeting of telomeric retrotransposons in Drosophila.

@article{Zhang2014CoordinationOT,
  title={Coordination of transposon expression with DNA replication in the targeting of telomeric retrotransposons in Drosophila.},
  author={Liang Zhang and Michelle L Beaucher and Yan Cheng and Yikang S Rong},
  journal={The EMBO journal},
  year={2014},
  volume={33 10},
  pages={1148-58}
}
In Drosophila, a group of retrotransposons is mobilized exclusively to telomeres in a sequence-independent manner. How they target chromosome ends is not understood. Here, we focused on the telomeric element HeT-A and characterized the cell cycle expression and cytological distribution of its protein and RNA products. We determined the timing of telomere replication by creating a single lacO-marked telomere and provide evidence suggesting that transposon expression and recruitment to telomeres… CONTINUE READING
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