Corpus ID: 8065080

Coordination between fission yeast glucan formation and growth requires a sphingolipase activity.

  title={Coordination between fission yeast glucan formation and growth requires a sphingolipase activity.},
  author={A. Feoktistova and P. Magnelli and C. Abeijon and P. P{\'e}rez and R. Lester and R. Dickson and K. Gould},
  volume={158 4},
  • A. Feoktistova, P. Magnelli, +4 authors K. Gould
  • Published 2001
  • Biology, Medicine
  • Genetics
  • css1 mutants display a novel defect in Schizosaccharomyces pombe cell wall formation. The mutant cells are temperature-sensitive and accumulate large deposits of material that stain with calcofluor and aniline blue in their periplasmic space. Biochemical analyses of this material indicate that it consists of alpha- and beta-glucans in the same ratio as found in cell walls of wild-type S. pombe. Strikingly, the glucan deposits in css1 mutant cells do not affect their overall morphology. The… CONTINUE READING
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