Coordinating cell proliferation and migration in the lens and cornea.
@article{Zelenka2008CoordinatingCP, title={Coordinating cell proliferation and migration in the lens and cornea.}, author={Peggy S. Zelenka and Parthasarathy Arpitha}, journal={Seminars in cell & developmental biology}, year={2008}, volume={19 2}, pages={ 113-24 } }
Migration is a complex process for epithelial tissues, because the epithelium must move as an intact sheet to preserve its barrier function. The requirement for structural integrity is met by coupling cell-to-matrix and cell-to-cell adhesion at the cellular level, and by coordinating cell proliferation and cell migration in the tissue as a whole. Proliferation is suppressed at the migrating cell front, allowing cells in this region to remain tightly packed while advancing rapidly. At the same… CONTINUE READING
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