Coordinating cell proliferation and migration in the lens and cornea.

@article{Zelenka2008CoordinatingCP,
  title={Coordinating cell proliferation and migration in the lens and cornea.},
  author={Peggy S. Zelenka and Parthasarathy Arpitha},
  journal={Seminars in cell & developmental biology},
  year={2008},
  volume={19 2},
  pages={
          113-24
        }
}
Migration is a complex process for epithelial tissues, because the epithelium must move as an intact sheet to preserve its barrier function. The requirement for structural integrity is met by coupling cell-to-matrix and cell-to-cell adhesion at the cellular level, and by coordinating cell proliferation and cell migration in the tissue as a whole. Proliferation is suppressed at the migrating cell front, allowing cells in this region to remain tightly packed while advancing rapidly. At the same… CONTINUE READING

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