Coordinating assembly of a bacterial macromolecular machine

  title={Coordinating assembly of a bacterial macromolecular machine},
  author={Fabienne F. V. Chevance and Kelly T Hughes},
  journal={Nature Reviews Microbiology},
The assembly of large and complex organelles, such as the bacterial flagellum, poses the formidable problem of coupling temporal gene expression to specific stages of the organelle-assembly process. The discovery that levels of the bacterial flagellar regulatory protein FlgM are controlled by its secretion from the cell in response to the completion of an intermediate flagellar structure (the hook–basal body) was only the first of several discoveries of unique mechanisms that coordinate… CONTINUE READING
Highly Influential
This paper has highly influenced 18 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS