Coordinate-Based Lead Location Does Not Predict Parkinson's Disease Deep Brain Stimulation Outcome

@inproceedings{Nestor2014CoordinateBasedLL,
  title={Coordinate-Based Lead Location Does Not Predict Parkinson's Disease Deep Brain Stimulation Outcome},
  author={Kelsey A. Nestor and Jacob D Jones and Christopher R. Butson and Takashi Morishita and Charles E. Jacobson and David A. Peace and Dennis Chen and Kelly Foote and Michael S. Okun},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Effective target regions for deep brain stimulation (DBS) in Parkinson's disease (PD) have been well characterized. We sought to study whether the measured Cartesian coordinates of an implanted DBS lead are predictive of motor outcome(s). We tested the hypothesis that the position and trajectory of the DBS lead relative to the mid-commissural point (MCP) are significant predictors of clinical outcomes. We expected that due to neuroanatomical variation among individuals, a simple… CONTINUE READING
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