Cooperative interactions in hexokinase D ("glucokinase"). Kinetic and fluorescence studies.


Hexokinase D, also called hexokinase IV or glucokinase, is the isoenzyme characteristic of liver. In spite of its common name of glucokinase it phosphorylates also other sugars besides glucose; in particular, it phosphorylates fructose with similar specificity to that shown by the other hexokinases. Although hexokinase D is a monomeric protein it displays… (More)


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