Cooperative function of POU proteins and SOX proteins in glial cells.

  title={Cooperative function of POU proteins and SOX proteins in glial cells.},
  author={Kirsten Kuhlbrodt and Beate Herbarth and Elisabeth Sock and Janna Enderich and Irm Hermans-Borgmeyer and Michael Wegner},
  journal={The Journal of biological chemistry},
  volume={273 26},
Glial cells of the oligodendrocyte lineage express several highly related POU proteins including Tst-1/Oct6/SCIP and Brn-1. Tst-1/Oct6/SCIP, but not Brn-1 efficiently cooperated with Sox10, the only SRY box protein so far identified in oligodendrocytes. Here we show that, in addition to Sox10, cells of the oligodendrocyte lineage contain significant amounts of the related SRY box proteins Sox4 and Sox11. During development, Sox11 was strongly expressed in the central nervous system. It was… CONTINUE READING
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  • Hermans-Borgmeyer, Beate Herbarth, Elisabeth Sock, Janna Enderich, Irm
  • Glia
  • 1990

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