Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways.

@article{Delaney2006CooperativeCO,
  title={Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways.},
  author={Joseph R. Delaney and Svenja St{\"o}ven and Hanna Uvell and Kathryn V Anderson and Ylva Engstr{\"o}m and Marek Mlodzik},
  journal={The EMBO journal},
  year={2006},
  volume={25 13},
  pages={3068-77}
}
Jun N-terminal kinase (JNK) signaling is a highly conserved pathway that controls both cytoskeletal remodeling and transcriptional regulation in response to a wide variety of signals. Despite the importance of JNK in the mammalian immune response, and various suggestions of its importance in Drosophila immunity, the actual contribution of JNK signaling in the Drosophila immune response has been unclear. Drosophila TAK1 has been implicated in the NF-kappaB/Relish-mediated activation of… CONTINUE READING

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