Cooperative binding of Tn3 resolvase monomers to a functionally asymmetric binding site


BACKGROUND The inverted repeat is a common feature of protein-binding sites in DNA. The two-fold symmetry of the inverted repeat corresponds to the two-fold symmetry of the protein that binds to it. In most natural inverted-repeat binding sites, however, the DNA sequence does not have perfect two-fold symmetry. Our study of how a site-specific recombinase… (More)
DOI: 10.1016/S0960-9822(95)00208-9


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