Cooperative anti-Candida effects of lactoferrin or its peptides in combination with azole antifungal agents.

@article{Wakabayashi1996CooperativeAE,
  title={Cooperative anti-Candida effects of lactoferrin or its peptides in combination with azole antifungal agents.},
  author={Hiroyuki Wakabayashi and Shigeru Abe and Takafumi Okutomi and Shigeru Tansho and Kouzou Kawase and Hideyo Yamaguchi},
  journal={Microbiology and immunology},
  year={1996},
  volume={40 11},
  pages={
          821-5
        }
}
The effects of lactoferrin (LF), an antimicrobial protein secreted in body fluids, and its peptides in combination with azole antifungal agents were investigated by the micro-broth-dilution method in a study of Candida albicans. In the case of LF, its pepsin hydrolysate (LFhyd) or the LF-derived antimicrobial peptide Lactoferricin B (LF-B), the concentrations required to inhibit the growth of Candida decreased in the presence of relatively low concentrations of clotrimazole (CTZ). The minimum… CONTINUE READING
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