Cooperative and independent functions of FGF and Wnt signaling during early inner ear development


In multiple vertebrate organisms, including chick, Xenopus, and zebrafish, Fibroblast Growth Factor (FGF) and Wnt signaling cooperate during formation of the otic placode. However, in the mouse, although FGF signaling induces Wnt8a expression during induction of the otic placode, it is unclear whether these two signaling pathways functionally cooperate… (More)
DOI: 10.1186/s12861-015-0083-8


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