Cooperation of Liver Cells in Health and Disease

  title={Cooperation of Liver Cells in Health and Disease},
  author={Zbigniew Kmie{\'c}},
  journal={Advances in anatomy, embryology, and cell biology},
  pages={III-XIII, 1-151}
The liver lobule is formed by parenchymal cells, i.e., hepatocytes and nonparenchymal cells. In contrast to hepatocytes that occupy almost 80% of the total liver volume and perform the majority of numerous liver functions, nonparenchymal liver cells, which contribute only 6.5% to the liver volume, but 40% to the total number of liver cells, are localized in the sinusoidal compartment of the tissue. The walls of hepatic sinusoid are lined by three different cell types: sinusoidal endothelial… CONTINUE READING
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