Cooperation between the human T-cell leukemia virus type-1 p30(II) protein and host cellular factors during oncogenic transformation and retroviral carcinogenesis

Abstract

The human T-cell leukemia virus type-1 (HTLV-1) pXencoded accessory factors, p30II and Hbz, suppress proviral gene expression and help to maintain latency as a prerequisite for the development of adult T-cell leukemia/lymphoma (ATLL). Our laboratory is studying how these viral proteins influence host cellular gene expression and signaling which may… (More)
DOI: 10.1186/1742-4690-11-S1-P95

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